Sufferers with bacterial pneumonia who’ve a penicillin allergy usually tend to have worse medical outcomes, a brand new research discovered.
Researchers hypothesized that as a result of sufferers having a PCN allergy label could expertise a delay in antibiotic administration and will find yourself receiving different and broader-spectrum antibiotic regimens for bacterial pneumonia, such sufferers would have an elevated threat for worse medical outcomes. To check this speculation, they leveraged a big population-based database to discover the doable results of the PCN allergy label on outcomes. The researchers additionally examined patterns of antibiotic use in these sufferers and the potential hostile results of antimicrobial remedy.
The investigators used TriNetX — a web-based instrument used for inhabitants cohort analysis — to establish grownup sufferers with and with out a PCN allergy label who had been recognized with bacterial pneumonia. The two affected person cohorts had been matched with respect to baseline demographics and persistent medical situations, with every cohort together with 68,748 sufferers. Learn extra right here.