In at this time’s publish, we’re going to stroll via the historical past of epinephrine, the varied vessels that carry this drug, and what’s on the horizon for this life-saving know-how.
First, let’s discuss what it’s.
Epinephrine is the drug type of adrenaline: a hormone naturally produced within the physique. Adrenaline is launched from the adrenal glands when your physique is in “struggle or flight” mode and perceives a menace.
For the meals allergy neighborhood, this remedy has life-saving potential and is the primary line of protection for treating anaphylaxis—a life-threatening allergic response marked by constricted airways that happens when an over-release of histamine and different chemical compounds flood the physique.
The Historical past of the EpiPen
Within the Seventies, auto-injector know-how was developed for army use as an antidote to nerve fuel. This breakthrough led to the creation of the EpiPen, the primary epinephrine auto-injector.
In 1987, the FDA authorized the EpiPen and the corporate was finally acquired by Mylan, a pharmaceutical firm that companions with Pfizer to provide the product. For a time, the EpiPen was the one epinephrine auto-injector in the marketplace—that has since modified.
The Rise of Competitors
There are 4 principal epinephrine auto-injector manufacturers in the marketplace at this time: EpiPen, Auvi-Q, Adrenaclick, and Symjepi. All of them are available in packs of two and have a shelf lifetime of round 6-12 months.
Every is designed with a spring-loaded, one-time-use needle to inject a dose of both 0.15mg or 0.30mg of epinephrine into an individual’s thigh. Why the thigh? Study it right here!
As well as, they’re moveable and meant to be carried round always for many who are prone to an anaphylactic response. Even with all of their similarities, every model does have not less than one key differentiator they will tout: