Meals protein-induced enterocolitis syndrome (FPIES) occurs when there’s irritation within the small and huge gut brought on by an immune response to a meals. This causes repeated vomiting and diarrhea that clears up when the meals is faraway from the eating regimen.
Indicators of FPIES can embrace pale or ashen pores and skin and sleepiness or weak point. FPIES doesn’t have typical signs of allergic reactions, equivalent to itching, hives, swelling, coughing, or wheezing.
Oct. 14, 2025, Is International FPIES Day
Consultants imagine round 900,000 folks in america have FPIES.1 It may be arduous to diagnose. There are not any checks for FPIES. Medical doctors should make a analysis primarily based on signs.
Lots of the signs can appear like different diseases, equivalent to a abdomen bug. However the affect could be severe – particularly in infants and toddlers – as a result of it may well trigger severe dehydration, failure to thrive, and even shock. Due to this, it’s necessary to unfold consciousness about FPIES.
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For those who suppose you or your little one might have FPIES, see a board-certified allergist for a analysis, if attainable.
Study extra about FPIES.
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Reference
1. Nowak-Wegrzyn A, Warren CM, Brown-Whitehorn T, Cianferoni A, Schultz-Matney F, Gupta RS. Meals protein-induced enterocolitis syndrome within the US population-based research. J Allergy Clin Immunol. 2019 Oct;144(4):1128-1130. doi: 10.1016/j.jaci.2019.06.032. Epub 2019 Jul 6. PMID: 31288044; PMCID: PMC7923683.
